KMID : 0900220170240020094
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´ëÇѺñ°úÇÐȸÁö 2017 Volume.24 No. 2 p.94 ~ p.103
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Effect of Positional therapy on Patients with Obstructive Sleep Apnea: Meta-Analysis
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Lee Eun-Sang
Choi Ji-Ho Lee Bo-Ra Jung Jae-Hyun Seon Sang-Woo Lee Seung-Jae Kim Hyo-Jun Lee Jae-Yong
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Abstract
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Background and Objectives: Positional therapy is a therapeutic method for obstructive sleep apnea (OSA). However, little is known about the effectiveness of positional OSA treatment based on meta-analysis. Therefore, we undertook a review and meta-analysis of studies to assess the effect of positional therapy on OSA.
Subjects and Method: We searched PubMed (Medline), OVID Medline, EMBASE, Cochrane Library, SCOPUS, KoreaMed, MedRIC, and KSI KISS using the key words ¡°obstructive sleep apnea¡± and ¡°positional therapy¡±. To estimate the effect of positional OSA therapy, we analyzed the ratio of means (ROM) for pre- and post-treatment polysomnographic data including apnea-hypopnea index (AHI), lowest oxygen saturation, arousal index, and sleep efficiency.
Results: Finally, twenty two studies from 21 papers were included in the meta-analysis. Positional therapy significantly decreased AHI by 54.1% [ROM, 0.459; 95% confidence interval (CI), 0.394 to 0.534] and increased lowest oxygen saturation by 3.3% (ROM, 1.033; 95% CI, 1.020 to 1.046). However, positional therapy did not significantly change arousal index (ROM,0.846; 95% CI, 0.662 to 1.081) or sleep efficiency (ROM, 1.008; 95% CI, 0.990 to 1.027).
Conclusion: Positional therapy significantly improves respiratory parameters including AHI and lowest oxygen saturation in patients with OSA.
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KEYWORD
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Obstructive sleep apnea, Positional therapy, Polysomnography, Apnea-hypopnea index, Lowest oxygen saturation
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